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Potential Applications of Nanocellulose-Containing Materials in the Biomedical Field

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dc.contributor.authorHalib, Nen_US
dc.contributor.authorPerrone, Fen_US
dc.contributor.authorCemazar, Men_US
dc.contributor.authorDapas, Ben_US
dc.contributor.authorFarra, Ren_US
dc.contributor.authorAbrami, Men_US
dc.contributor.authorChiarappa, Gen_US
dc.contributor.authorForte, Gen_US
dc.contributor.authorZanconati, Fen_US
dc.contributor.authorPozzato, Gen_US
dc.contributor.authorMurena, Len_US
dc.contributor.authorFiotti, Nen_US
dc.contributor.authorLapasin, Ren_US
dc.contributor.authorCansolino, Len_US
dc.contributor.authorGrassi, Gen_US
dc.contributor.authorGrassi, Men_US
dc.date.accessioned2024-05-29T02:55:21Z
dc.date.available2024-05-29T02:55:21Z
dc.date.issued2017
dc.description.abstractBecause of its high biocompatibility, bio-degradability, low-cost and easy availability, cellulose finds application in disparate areas of research. Here we focus our attention on the most recent and attractive potential applications of cellulose in the biomedical field. We first describe the chemical/structural composition of cellulose fibers, the cellulose sources/features and cellulose chemical modifications employed to improve its properties. We then move to the description of cellulose potential applications in biomedicine. In this field, cellulose is most considered in recent research in the form of nano-sized particle, i.e., nanofiber cellulose (NFC) or cellulose nanocrystal (CNC). NFC is obtained from cellulose via chemical and mechanical methods. CNC can be obtained from macroscopic or microscopic forms of cellulose following strong acid hydrolysis. NFC and CNC are used for several reasons including the mechanical properties, the extended surface area and the low toxicity. Here we present some potential applications of nano-sized cellulose in the fields of wound healing, bone-cartilage regeneration, dental application and different human diseases including cancer. To witness the close proximity of nano-sized cellulose to the practical biomedical use, examples of recent clinical trials are also reported. Altogether, the described examples strongly support the enormous application potential of nano-sized cellulose in the biomedical field.en_US
dc.identifier.doi10.3390/ma10080977
dc.identifier.issn1996-1944
dc.identifier.issue8
dc.identifier.scopusWOS:000408731600131
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/11522
dc.identifier.volume10
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherMDPIen_US
dc.relation.ispartofMaterialsen_US
dc.sourceWeb Of Science (ISI)
dc.subjectcelluloseen_US
dc.subjectwound healingen_US
dc.subjectbone-cartilage regenerationen_US
dc.subjectdental applicationen_US
dc.subjectsiRNAen_US
dc.subjectdrug-cell deliveryen_US
dc.titlePotential Applications of Nanocellulose-Containing Materials in the Biomedical Fielden_US
dspace.entity.typePublication

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