Mohd Kashim M.I.A.Hasim N.A.Othaman R.Yahaya M.Z.Khalid R.Samsudin M.A.Mat Zin D.M.2024-05-282024-05-282017126603910.17576/jsm-2017-4610-152-s2.0-85039968031https://www.scopus.com/inward/record.uri?eid=2-s2.0-85039968031&doi=10.17576%2fjsm-2017-4610-15&partnerID=40&md5=f01afa3aea5004f3f6af7394fc1bd1d3https://oarep.usim.edu.my/handle/123456789/8502Food and drink that were good (Halalan Toyyiban) is a compulsory in Islam. In this modern era, a concern was raised over the halal status of blood plasma that is widely used especially in the food industry. The objective of this study was to investigate the usefulness, advantages and disadvantages of the blood plasma as well as the views of Islamic scholars on this issue. The study was conducted using descriptive literature review. The study found that blood plasma has the ability to dissolve and high emulsifying, low viscosity and the ability to form a strong gel. Besides, it can improve the texture and be a binder in the production of modern food. It is a cheap alternative protein as fat substitute to be use in the production of low-fat meat products. Despite of the fact, the study found blood plasma contains various microorganisms and potentially harmful products of toxins and blood protein. In fact, products containing blood plasma is likely to cause allergy-induced protein content of blood. Now, there are a variety of detection methods that can be used to detect blood plasma in order to determine the halal status of food. There are two views regarding the legal use of blood plasma, first, the use of blood plasma in food products are allowed if it had a perfect process of changes, istihalah. Meanwhile a second opinion, to ban the blood plasma products as it has undergone an imperfect process of change, (istihalah fasidah) which results in the end material categorized as Haram. Therefore, law determination (Hukum) of istihalah in the production of blood plasma must meet the requirements of Islamic law while ensuring that the relevant legal issue is not outdated.en-USAdvantagesBlood plasmaDisadvantageHalalIstihalahArticle177917874610