Muhamad Rafiqi Hehsan‘Imran Mohd PazudinMuhammad ‘Afif RosdinWan Athirah Wan IzudinAn Nisa Yustisia RNisya Oktia NahdahZulkifli Dahalan2024-05-292024-05-2920232023-10-4Hehsan, M. R., Mohd Pazudin, I. ., Rosdin, M. A., Wan Izudin, W. A. ., Yustisia, A. N. ., Nahdah, N. O. ., & Dahalan, Z. . (2023). Human Stem Cell Transplantation: An Overview Of The Islamic Perspective’s Ethical Issues In Malaysia. Journal of Fatwa Management and Research, 28(3), 1-20. https://doi.org/10.33102/jfatwa.vol28no3.5150127-888610.33102/jfatwa.vol28no3.515https://jfatwa.usim.edu.my/index.php/jfatwa/article/view/515https://oarep.usim.edu.my/handle/123456789/13842/ VOL. 28 NO. 3Stem cells have unprecedented promise for treating disorders that are not amenable to conventional treatment because of their special capacity to maintain, replenish, and repair all tissue types. Stem cell research is currently surrounded by several pressing ethical and challenges as a result of the quick development of biotechnology. Therefore, the purpose of this study is to find out the ethical issues regarding the use of stem cells and correlate from an Islamic perspective, focusing on Malaysia. In this review, we outline an overview of the most significant ethical issues with stem cell application that the community especially Muslimsshould be aware of. The study applied a library-based methodology and gathered data about stem cells, their use, ethical concerns, and Islamic law with an emphasis on Malaysia from a range of sources, including books, websites and journals. The findings demonstrated that there are three main areas of ethical concern for stem cell technology from an Islamic perspective: human embryonic stem cells, stem cells used for aesthetic purposes, and stem cells used for therapeutic medicine. We attempted to correlate Malaysia's perspective with some of the Islamic perspective's points on all ethical concerns. We discovered that there are certain arguments towards every ethical issue from an Islamic perspective, and we tried to compare it to the perspective from Malaysia. Both the use of current ethical frameworks and careful evaluation from an Islamic perspective are important as this vast and diverse area of stem cell technology progresses, especially in Malaysia.en-USStem cell, ethical, Islamic, MalaysiaArticle120283