Idrose A.M.Juliana N.Azmani S.Yazit N.A.A.Muslim M.S.A.Ismail M.Amir S.N.2024-05-292024-05-2920208921997https://doi.org/10.1016/j.jvoice.2020.06.0312-s2.0-85088651974https://www.scopus.com/inward/record.uri?eid=2-s2.0-85088651974&doi=10.1016%2fj.jvoice.2020.06.031&partnerID=40&md5=e94a7abe5e554a223aa5d7cea4283ff4https://www.jvoice.org/article/S0892-1997(20)30246-0/fulltexthttps://oarep.usim.edu.my/handle/123456789/10453Copyright © 2020 The Voice Foundation. Published by Elsevier Inc. All rights reserved.At high altitude, low oxygen partial pressure predisposes human body to hypobaric hypoxia that may lead to high-altitude illness. Currently, singing had been used for rehabilitation of patients with lung diseases but its role in high-altitude low oxygen environment is still scarce. This study aims to examine the effect of singing in improving oxygen saturation at different levels of high altitudes in a hypobaric chamber. Eight healthy volunteers were assigned to three interventions at three simulated altitudes (sea level, 3000 m and 5000 m). The oxygen saturation (SpO2) was measured via pulse oximetry under three conditions: no singing (NS), singing aloud (SA), and singing silently (SS). The “birthday song” was used as the standard song for 4 minutes. At sea level, mean NS SpO2 was 97.75% ± 1.04%. With SS, the level increased to 98.25% ± 1.04%. Mean SA SpO2 increased to 98.38% ± 0.92% (P < 0.05). At 3000 m, mean NS SpO2 was 92.75% ± 3.73% and rose to 94.50% ± 2.51% and 94.63% ± 2.00% respectively with SA and SS (P < 0.05). At 5000 m, NS level of 79.88P ± 3.60% increased to 82.13 ± 5.87 and 82.88% ± 7.12% with SA and SS respectively (P < 0.05). The repeated measure ANOVA showed significant difference for altitude (P < 0.001) and intervention (P = 0.05). In conclusion, singing both either “aloud” or “silently” significantly increased the level of SpO2 in simulated high altitude at 3000 m and above. The study suggests that singing as a potential intervention to improve oxygen saturation at high altitudes. Study with larger sample in hypobaric chamber as well as in real environment is recommended. © 2020 The Voice Foundationen-USAcute Mountain Sickness (AMS)HypobaricHypoxiaSingingOxygen levelArticle