Muslimah IthninKhairun Nain Nor AripinNadia Mohd EffendyNorsham Juliana Binti NordinNadeeya'ayn Umaisara Binti Mohamad NorMohd Dzulkhairi Bin Mohd Rani2024-05-292024-05-2920212021-10-51823-6782447-3010.32802/asmscj.2020.437https://oarep.usim.edu.my/handle/123456789/10598Metabolic syndrome is a cluster of conditions that increase the risk of developing chronic diseases. This paper aims to assess the data on metabolic syndrome among indigenous Orang Asli in Malaysia. Searches were carried out using electronic databases of CINAHL, Medline, PubMed, and Scopus using predefined keywords. Cross-sectional studies of metabolic syndrome using any clinical diagnosis criteria among adult Orang Asli in Peninsular Malaysia included. Fifteen studies with these criteria were selected, five with metabolic syndrome studies. The general prevalence (weighted mean) of metabolic syndrome in Orang Asli was 26.3% (range: 12.0–39.8). Metabolic syndrome was more frequent in females (30.0%) than in males (19.3%). The most common components of metabolic syndrome were low HDL-C levels (41.0%) and hypertension (33.7%). For abdominal obesity, high triglycerides, and abnormal glycemia, the prevalence was; 24.6%, 21.5%, and 14.0%, respectively. Conclusively, the present systematic review brings us closer to an understanding of the prevalence of metabolic syndrome among this vulnerable population. The methodological differences among the studies published limit a joint analysis of their results. Nevertheless, finding from this review shows their high prevalence of the metabolic syndrome is comparable with other ethnic groups in Malaysia that requires immediate attention from all related parties.enindigenous; orang asli; adult; Malaysia; metabolic syndrome; prevalenceArticle11115