Em SutrisnaSri WahyuniDevi Usdiana RNoor Fadzilah ZulkifliNazefah Abd HamidFarah Wahida HarunSiti Salhah OthmanDzulfadli Rosli2025-12-042025-12-042025-09-05Em Sutrisna, Sri Wahyuni, Devi Usdiana R, Noor Fadzilah Zulkifli, Nazefah Abd Hamid, Siti Salhah Othman, Farah Wahida Harun, Dzulfadli Rosli (2025). Antibacterial effect of Pylantus niruri L. (Meniran) from Indonesia toward Staphylococcus epidermidis and Phytochemical Screening. Research Journal of Pharmacy and Technology, 18(9), 4477–4481. https://doi.org/10.52711/0974-360x.2025.006420974-360X10.52711/0974-360X.2025.00642https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-9-62https://oarep.usim.edu.my/handle/123456789/28141Indexed<jats:p>Background: In Indonesia there is no antibacterial medicine based on Indonesian medicinal plants Pylantus niruri L. (Meniran) is allegedly to have an antibacterial effect. Objective: This study aims to explore the antibacterial effects of the 96% ethanolic extract of P.niruri and to determine it’s TLC [Thin layer chromatography] Methods: The test design is an invitro study with diffusion and well methods. Bacteria used is S.epidermidis. The plant also performed phytochemical screening to determine the plant content that was suspected to have an antibacterial effect and continued thin layer chromatography. Results: The 96% ethanolic extract of P.niruri at concentrations of 100; 50; 25; 12.5 and 6,125% have an antibacterial effect with inhibition zones of 12,5;18,41; 12,31; 11,09 and 8,83mm. Conclusion: P niruri L. has potency antibacterial toward S. epidermidis</jats:p>en-USMeniran P.niruri Staphylococcus epidermidis Antibacterial.journal-article189