Dalal M. Ibrahim,Dalal M. IbrahimJuliana JumalFarah Wahida Harun2024-05-282024-05-282015--Middle-East Journal of Scientific Research 23 (12): 2946-2951, 2015 ISSN 1990-9233 © IDOSI Publications, 2015 DOI: 10.5829/idosi.mejsr.2015.23.12.228791990-9233422-910.5829/idosi.mejsr.2015.23.12.22879https://www.idosi.org/mejsr/mejsr23(12)15/20.pdfhttps://oarep.usim.edu.my/handle/123456789/4753Considerable interest has been aroused for copper complexes of coumarins due to their wide variety of biological activity. Three copper complexes of coumarin; A1, A2 and A3 were synthesized and evaluated for antitumor activity by using MTT assay. These complexes show antitumor activity against breast cancer MCF7 with IC values of 1.87, 1.87 and 30?g/ml respectively and exhibit 50 antitumor activity against lung cancer A549 with IC50 values of 7.5, 15 and 1.87?g/ml respectively.enCoumarin;Copper complexes;AntitumorArticle294629512312