Browsing by Author "Baird M.A."

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Some of the metrics are blocked by your 
    consent settings
    Publication
    Gut bacteria characteristic of the infant microbiota down-regulate inflammatory transcriptional responses in HT-29 cells
    (Academic Press, 2020)
    Pathmanathan S.G.
    ;
    Lawley B.
    ;
    McConnell M.
    ;
    Baird M.A.
    ;
    Tannock G.W.
    ;
    Faculty of Medicine and Health Sciences
    ;
    University of Otago
    ;
    Universiti Sains Islam Malaysia (USIM)
    Immuno-modulatory effects of infant gut bacteria were tested on poly(I:C) stimulated HT-29 intestinal epithelial cells. Blautia producta, Bacteroides vulgatus, Bacteroides fragilis and Bacteroides thetaiotaomicron decreased transcription of poly(I:C)-induced inflammatory genes. Modulation of basal level and poly(I:C)-induced IL-8 secretion varied between bacterial species, and between heat treated and non-heat treated bacterial cells.