Browsing by Author "Dalal M. Ibrahim,"

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    Publication
    Evaluation Of Antitumor Activity Of Copper Complexes Of Coumarin In Breast And Lung Cancer
    (IDOSI Publications, 2015)
    Dalal M. Ibrahim,
    ;
    Juliana Jumal
    ;
    Farah Wahida Harun
    Considerable interest has been aroused for copper complexes of coumarins due to their wide variety of biological activity. Three copper complexes of coumarin; A1, A2 and A3 were synthesized and evaluated for antitumor activity by using MTT assay. These complexes show antitumor activity against breast cancer MCF7 with IC values of 1.87, 1.87 and 30?g/ml respectively and exhibit 50 antitumor activity against lung cancer A549 with IC50 values of 7.5, 15 and 1.87?g/ml respectively.