Background: Neurological manifestations in Systemic Lupus Erythematous (SLE) varies and commonly affects the Central Nervous System (CNS) rather than the peripheral nervous system. Neuropsychiatric or CNS manifestation can be as high as 24-54%, whereas the peripheral nervous system involvement is lower around 5-27%. Chronic Inflammatory Demyelinating Polyradiculopathy (CIDP) is one of the three commonest peripheral nervous system involvements in SLE patients and results with severe debilitating effects. However, it is rarely reported. Methods: A retrospective review of all SLE patients that were diagnosed with CIDP between 2000 and 2015 was done under follow up at our center that were diagnosed with CIDP between 2000 and 2015. We reviewed their medical records and analyzed their clinical presentation, investigations, treatment instituted, response to therapy and any neurological sequealae. Results: A total of 512 case notes were reviewed. Of these 4 patients presented with CIDP (3 females, 1 male) aged between 26 to 46 years old. Three presented with transverse myelitis and the other one with acute motor and sensory axonal neuropathy. All patients were treated with high dose corticosteroids, three patients received cyclophosphamide whilst the other patient was induced with mycophenolate mofetil. Complete recovery was seen in one patient, two had persistent but improving numbness and the other one had a residual weakness. Conclusion: Peripheral nervous system involvement in SLE can result in serious debilitating effects. Early diagnosis and treatment are crucial in limiting the neurological sequealae.

Angiosarcoma is a rare, malignant vascular endothelium neoplasm with poor prognosis. Cutaneousangiosarcoma makes up a majority of its presentation. Diagnosis is often delayed due to the nature ofits clinical presentation. We report 3 cases of cutaneous angiosarcoma to focus on the importance ofbiopsy site selection in securing the histopathological diagnosis.

Possessing, processing and distributing marijuana or cannabis is illegal in many countries, especially Malaysia. Individuals guilty of that act may face imprisonment and even a death sentence even though cannabis oil and its derivative in the medical field have become more prevalent and have been legalised in many countries and recently in Thailand, a Malaysian neighbour. The Malaysian government is also evaluating and detailing the users and will have its final stand by 2022. Various studies proved marijuana to be beneficial for specific medical conditions. Thus, this paper aims to explore the current evidence of the use of medical marijuana from medical, legal and Islamic law views. The literature search was conducted online using various platforms such as google scholar, Pubmed, ScienceDirect, Medline EBSCO host and DOAJ. The search term includes "medical marijuana", "cannabis oils", "cannabis law", "Medical Marijuana Law", "cannabis"," marijuana legal", and "Islamic perspective". The content further discusses the medical perspective of marijuana, including its pharmacology, potential benefits and risks. In addition, the legal and Islamic views on medical marijuana, especially regarding the medical marijuana laws and Islamic rulings on marijuana use, will also be discussed.