Introduction: Chronic histiocytic intervillositis (CHI) is a rare placental lesion strongly associated with recurrent miscarriages and fetal losses. It requires histopathological diagnosis and can only be made after delivery of the products of conception (POC). We describe a case of CHI in a 41-yearold lady with a 16-year history of thirteen recurrent consecutive first trimester miscarriages. Case report: The patient is a 41-year-old lady who suffered first trimester miscarriages in all her thirteen pregnancies. The relevant clinical investigations revealed neither significant nor helpful findings in determining the cause of recurrent miscarriages. Histological findings in each except one of the submitted conceptual tissue showed similar features of histiocytic aggregates primarily within the intervillous spaces, a characteristic description of CHI. One of the samples showed degenerative changes. Discussion: Practicing pathologists are not familiar with the histological features of CHI and this may be a potential pitfall in routine examination of POCs. Recognising this entity allows for accurate diagnosis and hence better management. The aetiology remains unclear, although an immunopathological basis are being explored.

Introduction: Maternal Floor Infarction (MFI) is an uncommon pathological entity characterised by the presence of massive and diffuse perivillous fibrinoid material in the maternal surface of the placenta. It was first described in the 1960s. MFI has clear associations with intrauterine fetal demise, IUGR and recurrent pregnancy losses. We would like to share two cases of MFI, which had similar clinical presentations. Case reports: Case 1: A 31-year-old lady who is in her sixth pregnancy and at 32 weeks of gestation. She has a history of three intrauterine fetal deaths and two live births. Her recent pregnancy was complicated with IUGR, oligohydramnious and absence of end diastolic flow on Doppler. Case 2: A 34-year-old lady who is in her third pregnancy and at 35 weeks of gestation. Similarly she had IUGR and oligohydramnios. In both cases, the babies were delivered alive by caesarean sections. Tissue examination of both placentas showed extensive fibrin deposition on the decidual floor, extending up into the intervillous spaces with encasement of the villi amounting to MFI. Discussion and Conclusion: Although MFI is uncommon, it has significant perinatal morbidity and mortality with the risk of recurrence. In general, practicing pathologists are unfamiliar with MFI which is macroscopically and microscopically different from ischaemic infarcts. The etiology of MFI is unknown, but evidence support an alloimmune or autoimmune mechanism. Awareness of this old entity and recognizing them on placenta tissue sections would aid in management of future pregnancies and in the adequate follow up of the surviving infants