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Gut bacteria characteristic of the infant microbiota down-regulate inflammatory transcriptional responses in HT-29 cells

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dc.contributor.affiliationsFaculty of Medicine and Health Sciences
dc.contributor.affiliationsUniversity of Otago
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.authorPathmanathan S.G.en_US
dc.contributor.authorLawley B.en_US
dc.contributor.authorMcConnell M.en_US
dc.contributor.authorBaird M.A.en_US
dc.contributor.authorTannock G.W.en_US
dc.date.accessioned2024-05-29T01:59:50Z
dc.date.available2024-05-29T01:59:50Z
dc.date.issued2020
dc.descriptionAnaerobe Volume 61, February 2020, 102112en_US
dc.description.abstractImmuno-modulatory effects of infant gut bacteria were tested on poly(I:C) stimulated HT-29 intestinal epithelial cells. Blautia producta, Bacteroides vulgatus, Bacteroides fragilis and Bacteroides thetaiotaomicron decreased transcription of poly(I:C)-induced inflammatory genes. Modulation of basal level and poly(I:C)-induced IL-8 secretion varied between bacterial species, and between heat treated and non-heat treated bacterial cells.en_US
dc.description.natureFinal
dc.identifier.ArtNo102112
dc.identifier.CODENANAEF
dc.identifier.doi10.1016/j.anaerobe.2019.102112
dc.identifier.isiWOS:000525325200021
dc.identifier.issn10759964
dc.identifier.pmid31629806
dc.identifier.scopus2-s2.0-85074504467
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85074504467&doi=10.1016%2fj.anaerobe.2019.102112&partnerID=40&md5=7fbd2075b78ffecbdaaef2ce655196f8
dc.identifier.urihttps://www.sciencedirect.com/science/article/abs/pii/S1075996419301842?via%3Dihub
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/10087
dc.identifier.volume61
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherAcademic Pressen_US
dc.relation.ispartofAnaerobeen_US
dc.sourceScopus
dc.subjectBacteroidesen_US
dc.subjectBlautiaen_US
dc.subjectHT-29en_US
dc.subjectpoly(I:C)en_US
dc.subjectRuminococcusen_US
dc.titleGut bacteria characteristic of the infant microbiota down-regulate inflammatory transcriptional responses in HT-29 cellsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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