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Dengue protease inhibition activity of selected malaysian medicinal herbs

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dc.FundingDetailsMinistry of Higher Education, Malaysia,�MOHE: TR001B-2014A,�UCG-0116/FPQS/30/14316,�PG101-2016A
dc.FundingDetailsAcknowledgements. This study was funded by the Ministry of Higher Education through the Trans Disciplinary Research Grant Scheme (TR001B-2014A), USIM C (PPP/ UCG-0116/FPQS/30/14316) and Postgraduate Research Grant, PPP (PG101-2016A).
dc.contributor.affiliationsFaculty of Quranic and Sunnah Studies
dc.contributor.affiliationsUniversity of Malaya (UM)
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.affiliationsUniversiti Sains Malaysia (USM)
dc.contributor.authorSalleh H.M.en_US
dc.contributor.authorChong S.-L.en_US
dc.contributor.authorOthman R.en_US
dc.contributor.authorHazni H.en_US
dc.contributor.authorAhmad K.en_US
dc.contributor.authorMohd Yusof M.Y.Z.en_US
dc.contributor.authorFauzi N.W.en_US
dc.contributor.authorWahab H.A.en_US
dc.contributor.authorLiew S.Y.en_US
dc.contributor.authorAwang K.en_US
dc.date.accessioned2024-05-29T01:56:39Z
dc.date.available2024-05-29T01:56:39Z
dc.date.issued2019
dc.descriptionTropical Biomedicine 36(2): 357–366 (2019)en_US
dc.description.abstractDengue fever is one of major health problem around the world including Malaysia. It is caused by the arthropode-borne flavivirus and transmitted by the bite of the Aedes aegypti or Aedes albopictus mosquito infected with one of the four dengue virus serotypes (DENV-1, DENV-2, DENV-3, or DENV-4). In this study, a screening exercise of various Malaysian medicinal plants showed that the extracts of Lawsonia inermis, Dryobalanops aromatica, Punica granatum, Zizyphus jujuba Lam. and Zingiber zerumbet exhibited potent inhibitory activity against NS2B-NS3 serine protease. The methanol extracts of Dryobalanops aromatica showed inhibition of 99.70 % at concentration of 200 �g/mL with IC50 value of 0.30 � 0.16 �g/mL. � 2019, Malaysian Society for Parasitology. All rights reserved.en_US
dc.description.natureFinalen_US
dc.identifier.epage366
dc.identifier.isiWOS:000475610700005
dc.identifier.issn1275720
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85071253546
dc.identifier.spage357
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85071253546&partnerID=40&md5=b1066057a4b5b46dbac2873cafcf1979
dc.identifier.urihttps://msptm.org/vol-36-no-2-june/
dc.identifier.urihttps://msptm.org/files/Vol36No2/357-366-Awang-K.pdf
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/9859
dc.identifier.volume36
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherMalaysian Society for Parasitologyen_US
dc.relation.ispartofTropical Biomedicineen_US
dc.sourceScopus
dc.titleDengue protease inhibition activity of selected malaysian medicinal herbsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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