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Applications of X-Chromosome Short Tandem Repeats for Human Identifica-tion: A Review

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Applications Of X-chromosome Short Tandem Repeats For Human Identification.pdf (743.98 KB)

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2023

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Brawijaya University

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Abstract

The forensic DNA profiling technique has tremendously contributed to forensic human identification, an important aspect in forensic investigations. In instances whereby comparison samples are unavailable, utilization of short tandem repeats of X chromosome (X-STRs) may prove useful to resolve complex kinship investigations involving missing persons and mass disasters. Despite such evidential values, the use of X-STRs during investigations remains scarce in many Southeast Asian countries including Malaysia, requiring concerted efforts for establishing forensic statistical support for its diverse populations (especially the admixture populations), standardizing core loci and procedure, improving the knowledge among practitioners as well as developing suitable standard operating procedure for incorporating X-STRs analysis in the overall DNA profiling framework. Hence, this review paper aims to highlight the developments, applications and population data of X-STRs, as well as its challenges and future insights for forensic casework.

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Vol. 13 No. 1 (page:193 – 218)

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Complex kinship, Forensic statistical parameters, Human identification, Population genetics, Short tandem repeats, X-chromosome

Citation

Naji Arafat Mahat, Aedrianee Alwi, Faezah Salleh, Seri Ishar, M. Kamaluddin, & Rashid, M. (2023). Applications of X-Chromosome Short Tandem Repeats for Human Identification: A Review. Journal of Tropical Life Science, 13(1), 193–218. https://doi.org/10.11594/jtls.13.01.19

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https://jtrolis.ub.ac.id/index.php/jtrolis/article/view/2567
 https://www.scopus.com/record/display.uri?eid=2-s2.0-85147953442&origin=resultslist&sort=plf-f&src=s&sid=3ba025d722693f219c07a75ee66fa2b1&sot=b&sdt=b&s=TITLE-ABS-KEY%28Applications+of+X-Chromosome+Short+Tandem+Repeats+for+Human+Identification%3A+A+Review%29&sl=125&sessionSearchId=3ba025d722693f219c07a75ee66fa2b1
 https://oarep.usim.edu.my/handle/123456789/10455

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