Publication: Concomitant Use Of Antipsychotics And Diuretic Accelerates The Hyponatremia Effect
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Date
2022
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
USIM Press
Abstract
We reported a case of severe symptomatic hyponatremia with a serum sodium level of 113 mmol/l after 2 weeks commencement of 2 types atypical antipsychotics; clozapine and amisulpiride with indapamide, a thiazide-like diuretic antihypertensive medication. Discontinuation of indapamide despite of continuation of his antipsychotics showed improvement in his serum sodium level. The aim of our case-report is to emphasize the life-threatening complication associated with the combination of agents that may cause hyponatremia. Both agents are known to cause electrolytes imbalance. Hence, close monitoring of the serum sodium is important during the treatment course.
Description
Vol. 8 (2022): Special Issue on Communicable and Non-Communicable Disease, Multidisciplinary Case Reports
Keywords
Hyponatremia, Schizophrenia, indapamide, Antipsychotics
Citation
Ismail, N., & Mohd Daud, T. I. (2022). Concomitant Use of Antipsychotics and Diuretic Accelerates the Hyponatremia Effect. Malaysian Journal of Science Health & Technology, 8, 28–30. https://doi.org/10.33102/mjosht.v8i.288