Publication:
Combination Effects Of Extracts From Different Parts Of Euphorbia Hirta On Staphylococcus Epidermidis And Shigella Sonnei

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Abstract

The different parts of Euphorbia hirta which are flowers, stems, leaves and roots showed high antibacterial activity against two strains of bacteria namely Staphylococcus epidermidis and Shigella sonnei. In this present study, attempt was made to evaluate the combination effects between each two different parts of E.hirta on those strains. The two different parts of plants combinations (which are flowers-stems, flowers-leaves, flowers-roots, stems-leaves, stems-roots and leaves-roots) were treated on each selected bacteria, while the single part treatments was served as the controls. Generally, there are four combination effects which are synergism, additive, antagonisms and indifference effects could be observed in this study. Synergism effect was only indicated for the combination treatments towards S. epidermidis. The highest synergism effect (89%) was exhibited from the treatment of flowers-leaves and stems-leaves on S. epidermidis. All the combination treatments on both bacteria indicated an additive effect with the highest effects (78%) showed by the treatment of flowers-leaves, flowers-roots, and leaves-roots towards S. sonnei. However, indifferent and antagonisms effects could be observed only in the combination treatments against S. sonnei. The highest indifference (67%) and antagonisms (22%) effects on S. sonnei, each was exhibited by the treatment with stems-leaves and flowersstems respectively.

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Euphorbia hirta, combination effects, Staphylococcus epidermidis, Shigella sonnei, synergism, additive

Citation

Asian Journal of Biochemical and Pharmaceutical Research Issue 4(Vol. 3) 2013 ISSN: 2231-2560