Publication: A new nano-worm structure from gold-nanoparticle mediated random curving of zinc oxide nanorods
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Date
2016
Authors
Veeradasan Perumal
Uda Hashim
Subash C.B. Gopinath
R. Haarindraprasad
P. Poopalan
Wei-Wen Liu
M. Ravichandran
S.R. Balakrishnan
A.R. Ruslinda
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Creating novel nanostructures is a primary step for high-performance analytical sensing. Herein, a new worm like nanostructure with Zinc Oxide-gold (ZnO/Au) hybrid was fabricated through an aqueous hydrothermal method, by doping Au-nanoparticle (AuNP) on the growing ZnO lattice. During ZnO growth, fine tuning the solution temperature expedites random curving of ZnO nanorods and forms nano-worms. The nano-worms which were evidenced by morphological, physical and structural analyses, revealed elongated structures protruding from the surface (length: 1 µm; diameter: ~100 nm). The appropriate peaks for the face centred cubic gold were (111) and (200), as seen from X-ray diffractogram. The strong interrelation between Au and ZnO was manifested by X-ray photoelectron spectroscopy. The combined surface area increment from the nanoparticle radii and ZnO nanorod random curving gives raise an enhancement in detection sensitivity by increasing bio-loading. ‘Au-decorated hybrid nano-worm’ was immobilized with a probe DNA from Vibrio Cholera and duplexed with a target which was revealed by Fourier Transform Infrared Spectroscopy. Our novel Au-decorated hybrid nano-worm is suitable for high-performance bio-sensing, as evidenced by impedance spectroscopy, having higher-specificity and attained femtomolar (10 fM) sensitivity. Further, higher stability, reproducibility and regeneration on this sensing surface were demonstrated.
Description
Biosensors and Bioelectronics
Volume 78, 15 April 2016, Pages 14-22
Keywords
Nano-worm, Nanorod, Zinc Oxide, Gold nanoparticle, DNA, Cholera
Citation
Veeradasan Perumal, Uda Hashim, Subash C.B. Gopinath, R. Haarindraprasad, P. Poopalan, Wei-Wen Liu, M. Ravichandran, S.R. Balakrishnan, A.R. Ruslinda, A new nano-worm structure from gold-nanoparticle mediated random curving of zinc oxide nanorods, Biosensors and Bioelectronics, Volume 78, 2016, Pages 14-22, ISSN 0956-5663, https://doi.org/.